DIARECT Newsletter

Dear Madam or Sir,

The world’s largest medical marketplace MEDICA will be held from November 20 – 23 this year.
We would like to take this opportunity to invite you to stop by our booth at Hall 1, Booth E19.

To schedule an appointment at any of the upcoming events or receive more information on the topics of this newsletter, please contact us at:

Tel: +49 761 47979 0
Email: orders@diarect.com

Pleasant reading!

The DIARECT team


New Borrelia sp. antigens

Lyme disease is a multisystemic infectious disease caused by Borrelia species. 
Borrelia is transmitted by the bite of infected ticks from the genus Ixodes. The various clinical manifestations in early disease stage include flu-like symptoms and a characteristic circular skin rash called erythema migrans. Left untreated, the disease is characterized by chronic infection of the joints, heart, and central nervous system. Delayed or inadequate treatment can lead to the serious late manifestations, which can be disabling and difficult to treat. 
DIARECT now offers a variety of recombinant Borrelia sp. antigens, expressed in and purified from either the E. coli or the baculovirus / insect cell expression system:


Update on DIARECT's myositis antigens

Inflammatory myopathies are characterized by the presence of inflammatory infiltrates within skeletal muscle. These idiopathic myopathies encompass a variety of both common and uncommon syndromes.
The common subtypes include adult polymyositis (PM) and dermatomyositis (DM), along with inclusion body myositis, childhood myositis, malignancy-associated myositis, and myositis in overlap with another autoimmune connective tissue disease.
To date, autoantibodies targeting eight of the 20 aminoacyl-tRNA synthetases have been identified, being found in up to 30% of sera from patients with myositis.
They are highly specific for this disorder and strongly associated with complicating lung disease.

DIARECT offers a growing range of polymyositis / dermatomyositis antigens, the newest product of which is Asparaginyl-tRNA Synthetase (KS):

The above mentioned antigens are produced in the baculovirus / insect cell expression system and all have a proven track record for quality and sensitivity.


DIARECT - Lumigen's New Distribution Partner

As of October 2013, DIARECT is selling the complete line of Lumigen chemiluminescent substrates including Western Blotting and ELISA substrates as well as the Lumigen HyPerBlu reagent
for the direct detection of hydrogen peroxide.
Lumigens' chemiluminescent reagents are used worldwide in automated systems for the chemiluminescent detection of alkaline phosphatase and horseradish peroxidase conjugates
and in ultrasensitive assays in the fields of life science research and human identity testing.
For further information on the complete range of chemiluminescent reagents, please visit our website at http://www.diarect.com and click on the Lumigen logo on the left.


SurModics StabilZyme Protein-Free Stabilizer

We are pleased to introduce SurModics StabilZyme® Protein-Free Stabilizer, the newest member of SurModics’ family of Protein Stabilizers and Blockers.
Assays have become increasingly sensitive in recent years. The protein stabilizers most commonly used to stabilize biomolecule activity often contribute
to interference and cross-reactivity leading to less reliable results. SurModics’ new StabilZyme Protein-Free Stabilizer (SZPF) delivers excellent retained activity -
a key performance factor - while eliminating the interference and cross-reactivity associated with protein-based stabilizers.
StabilZyme® Protein-Free Stabilizer
-       Stabilize biomolecule activity without protein
-       Eliminate unwanted interference and cross-reactivity caused by proteins
-       Designed for conjugated protein, antibody-coated particles, and unmodified proteins in solution

Percent retained activity is determined by dividing the absorbance units of the 37°C
accelerated sample by the absorbance units of the 4°C control. Arrhenius accelerated
stability projections for StabilZyme Protein-Free Stabilizer demonstrate approximately 86%
retained activity for greater than 2 years.


Upcoming Events - meet the DIARECT team

AMP Annual Meeting
Date: Nov. 14 - 16, 2013
Location: Phoenix, AZ, USA
Booth 201 (SurModics)

ACA 2013 Autoimmunity Congress Asia
Date: Nov. 20 - 22, 2013
Location: Hong Kong
Poster ACA-0159

Date: Nov. 20 - 23, 2013
Location: Düsseldorf, Germany
Booth 1E19

If you would like to meet a member of the DIARECT team, please contact us at:
Email        orders@diarect.com
Tel.           +49 761 47979 0

We are looking forward to meeting with you soon!


Distributor - North America

SurModics IVD

9924 West 74th Street
Eden Prairie, MN 55344  USA

Phone: +1 952 500 7200
Toll-free: +1 800 755 7793
Fax: +1 952 500 7201



Distributors - China
Biobridge Logo

Beijing Biobridge Bio-technology Inc.

Room 221, Fanghezhengyuan B Building
Guanghua Road 16
Tongzhou Industry Development District
Beijing 101113
P.R. China

Phone: +86 10 61507875
Fax: +86 10 61507837 808
Email: order@bjbiobridge.com.cn


Shanghai BioSun Sci&Tech Co., Ltd.

Room E2, 6F, Bldg. No.1
825 Zhaojiabang Road
Shanghai 200032
P.R. China

Phone: +86 21 54253791
Fax: +86 21 64280007
Email: biosun@biosun.cn




If you would like to receive more detailed information on DIARECT products, please follow this link to our contact and order form.

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