Sm (non recombinant; bovine)dsDNA (plasmid)DNA Topoisomerase I (Scl-70; full length)DNA Topoisomerase I (Scl-70; truncated)Centromere Protein A (CENP-A)Centromere Protein B (CENP-B)Ro/SS-A (60 kDa; recombinant)Ro/SS-A (60 kDa; non recombinant; bovine)Ro/SS-A (52 kDa)La/SS-BHistidyl-tRNA Synthetase (Jo-1)Threonyl-tRNA Synthetase (PL-7)Alanyl-tRNA Synthetase (PL-12)Mi-2SRP54U1-snRNP 68/70 kDaU1-snRNP AU1-snRNP CU-snRNP B/B´Proliferating Cell Nuclear Antigen (PCNA)PM/Scl100Ku (p70/p80)Ribosomal Phosphoprotein P0
Thyroglobulin (non recombinant)
| Cat. No. | Available in |  |
| 12200 | 0.1 mg | |
| 12201 | 1.0 mg | |
Data Sheet (english)Diseases:
Autoimmune Thyroiditis (e.g. Graves Disease, Hashimoto Thyroiditis)
Thyroglobulin (TG) represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consist of TG.
DIARECT produces native human thyroglobulin.
TG autoantibodies of IgG type have a prevalence of 80-85% in patients with Hashimoto thyroiditis and also a lower prevalence of 30-80% in patients with Graves' disease.