IA-2 (ICA 512)

Diabetes Mellitus

Product Code Quantity Product Name Downloads Data Sheet
13800
13801
0.1 mg
1.0 mg

Glutamate Decarboxylase 65 kDa (GAD65)

The 65kDa-enzyme glutamate decarboxylase (GAD65) catalyzes the decarboxylation of glutamate to gamma-aminobutyrate (GABA). In human cells, GAD65 localizes to the vicinity of the Golgi apparatus and vesicles containing GABA.
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20800
20801
0.05 mg
  0.5 mg

GAD65 biotinylated

Binding of biotin to streptavidin is one of the strongest non-covalent interactions known in nature. This feature is used in innovative bead-based technologies to improve diagnostics by investigating multiple targests in one sample or applying standard-procedures with high throughput capability. DIARECT's biotinylated GAD65 represents a further development of the established antigen.
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30500
30501
0.1 mg
1.0 mg

IA-2 (ICA 512)

Insulinoma-associated protein (IA-2), also called islet cell antigen 512 (ICA 512), is a catalytically inactive protein tyrosine phosphatase (PTP)-like protein and a major target of autoimmune response in diabetes mellitus. The long C-terminal intracellular tail, harbors the majority of autoantibody epitopes. IA-2 is expressed within secretory granules in neural, neuroendocrine and pancreatic islet cells.
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