IA-2 (ICA 512)
|Product Code||Quantity||Product Name||Downloads||Data Sheet|
|0.1 mg |
Glutamate Decarboxylase 65 kDa (GAD65)The 65kDa-enzyme glutamate decarboxylase (GAD65) catalyzes the decarboxylation of glutamate to gamma-aminobutyrate (GABA). In human cells, GAD65 localizes to the vicinity of the Golgi apparatus and vesicles containing GABA.
|0.05 mg |
GAD65 biotinylatedBinding of biotin to streptavidin is one of the strongest non-covalent interactions known in nature. This feature is used in innovative bead-based technologies to improve diagnostics by investigating multiple targests in one sample or applying standard-procedures with high throughput capability. DIARECT's biotinylated GAD65 represents a further development of the established antigen.
|0.1 mg |
IA-2 (ICA 512)Insulinoma-associated protein (IA-2), also called islet cell antigen 512 (ICA 512), is a catalytically inactive protein tyrosine phosphatase (PTP)-like protein and a major target of autoimmune response in diabetes mellitus. The long C-terminal intracellular tail, harbors the majority of autoantibody epitopes. IA-2 is expressed within secretory granules in neural, neuroendocrine and pancreatic islet cells.