Allergens

*Antigens associated with the following allergies*

Food

Product Code Quantity Product Name Downloads Data Sheet
52500
52501
0.1 mg
1.0 mg

Ara h 1.0101

Ara h 1.0101 is a seed storage protein from Arachis hypogaea (peanut) found in the cotyledon. It is a heat stable 7S vicilin-like globulin with a stable trimeric form that comprises 12 to 16% of the total protein in peanut extracts. The protein is one of the main storage proteins of the seed and therefore of high necessity during plant development.
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50100
50101
0.1 mg
1.0 mg

Ara h 2.0201

Ara h 2 consists of two isoforms, called Ara h 2.0101 and Ara h 2.0201. The second isoform contains other IgE epitopes and has similar but higher IgE binding than Ara h 2.0101 (81% vs. 77%) . Ara h 2.0201, generally known as the most important peanut allergen, is a conglutin storage protein and accounts together with Ara h 6.0101 for the majority of the IgE immune response.
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51900
51901
0.1 mg
1.0 mg

Ara h 6.0101

Ara h 6.0101 is a conglutin, belonging to the 2S albumin protein family. Together with Ara h 2.0201, it is considered one of the most potent elicitors of anaphylaxis. Both proteins contain multiple disulphide-bridged cysteine residues, resulting in a tightly coiled, heat-stable, protease resistant core structure.
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52000
52001
0.1 mg
1.0 mg

Ara h 9.0101

The lipid transfer protein (LTP) Ara h 9 is a small molecule with high resistance to digestion and heat denaturation. Several different LTPs have been identified as relevant allergens in plant foods and pollens and are often associated with severe reactions in addition to oral allergy syndrome.
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50500
50501
0.1 mg
1.0 mg

Gly m 4.0101

Glycine max (Gly m) 4.0101 is a soybean protein whose expression is induced under stress conditions like starvation giving rise to its alternative name starvation-associated message 22 (SAM 22) or stress-induced protein SAM22. It is a homologue of Betula verrucosa (Bet v) 1, a major birch pollen allergen.
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50600
50601
0.1 mg
1.0 mg

Gly m 5.0101

Upon germination, the Glycine max seed storage protein Gly m 5.0101 serves as carbon and nitrogen source for the developing seedling. This protein is also known as beta-conglycinin and belongs to the superfamily of 7 S globulins, also known as 7 S vicilins.

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51800
51801
0.1 mg
1.0 mg

Cor a 1.0401

Cor a 1.0401 represents the major hazelnut allergen from Corylus avellana. This pathogenesis-related protein, PR-10, belongs to the family of Bet v1 homologues and is closely related to the major hazel pollen allergen Cor a 1.0103.

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Grasses

Product Code Quantity Product Name Downloads Data Sheet
51300
51301
0.1 mg
1.0 mg

Phl p 1.0102

Phl p 1.0102 is a member of the beta-expansin family whose members are involved in the modification of the plant cell wall during developmental processes. It is a known allergen found in the pollen of Phleum pratense known allergen. Therefore, it is commonly known as pollen allergen Phl p 1.
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51400
51401
0.1 mg
1.0 mg

Phl p 2.0101

Phl p 2.0101 is a member of group II/III of grass pollen allergens. This protein represents a major allergen of Phleum pratense and is detected exclusively in the pollen and not in other plant tissues. In line with other Phleum pratense allergens, this protein is also named pollen allergen Phl p 2.
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51500
51501
0.1 mg
1.0 mg

Phl p 5.0203

Phl p 5.0203 is a protein found in the starch granules of Phleum pratense pollens that has been suggested to be involved in plant defense mechanism due to its RNAse activity. This protein is a member of the so-called group V allergens.
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51600
51601
0.1 mg
1.0 mg

Phl p 6.0101

Like other Phleum pratense allergens, Phl p 6.0101 has been reported to be exclusively detected in the pollen where it localizes with polysaccharide-containing wall precursor bodies, the so-called P-particles.  Based on its localization, this protein is also known as pollen allergen Phl p 6.
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52300
52301
0.1 mg
1.0 mg

Phl p 7.0101

Phl p 7.0101 is a minor, non-glycosylated, allergen of timothy grass pollen, recognizing serum IgE antibodies of grass pollen-sensitized individuals. It is a Ca2+-binding protein with high sequence homology to pollen proteins found in a number of other plants, therefore likely to cross-react with those.
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52400
52401
0.1 mg
1.0 mg

Phl p 12.0101

Like all profilins, minor grass pollen allergen Phl p 12.0101 is involved in cytoskeleton dynamics by binding to actin. Immunological cross-reactivity regarding IgE binding, among pollen profilins and profilins of plant-derived foods, is well known.
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Trees

Product Code Quantity Product Name Downloads Data Sheet
50700
50701
0.1 mg
1.0 mg

Aln g 1.0101

Aln g 1.0101 represents a major allergen of Alnus glutinosa and a member of the Bet v 1 family of allergens commonly found in plants of the order Fagales. This protein localizes to the pollen of Alnus glutinosa and is therefore also known as major pollen allergen Aln g 1.
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50800
50801
0.1 mg
1.0 mg

Aln g 4.0101

Aln g 4.0101 is an Alnus glutinosa protein that comprises two EF-hands and is found in the pollen. EF-hands are known for their ability to complex Calcium ions and to induce conformational changes. Alternatively, this allergen is known as polcalcin Aln g 4 or calcium-binding pollen allergen Aln g 4.
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50200
50201
0.1 mg
1.0 mg

Bet v 1.0101

The pollen of Betula verrucosa of the order Fagales is a major etiological agent of allergies in humans that comprises several different allergens. Bet v 1.0101 is one of these allergens and the name-giving protein for the Bet v 1 family of allergens.  This protein is also known as major pollen allergen Bet v 1-A.
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50300
50301
0.1 mg
1.0 mg

Bet v 2.0101

Bet v 2.0101 or profilin-1 is an allergen identified in the pollen of Betula verrucosa, a major cause of allergies in humans.  In eukaryotic cells, profilin binds to actin and is involved in the regulation of the cytoskeleton.
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52100
52101
0.1 mg
1.0 mg

Bet v 4.0101

Bet v 4.0101 is primarily expressed in mature birch (Betula verrucosa) pollen. It is a 9 kDa calcium-binding protein of 2-EF-hand type, which is represented in pollen of a wide range of plant species. This extensive cross-reactivity can serve as a marker allergen for plant polysensitization.
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52200
52201
0.1 mg
1.0 mg

Bet v 6.0102

Isoflavone reductases (IFRs), like birch pollen allergen Bet v 6.0102, have also been found in apple, pear, orange, mango, lychee and other plants. They are plant defense proteins and appear to be induced by plant stress, e.g. high salinity, freeze or drought.
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51200
51201
0.1 mg
1.0 mg

Car b 1.0109

Carpinus betulus is a member of the order Fagales, which also comprises Betula verrucosa.  Car b 1.0109 is a major pollen allergen and is a member of the Bet v 1 family allergens typically found in this order. Car b 1.0109 is an isoform of the pollen allergen Car b 1.
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51100
51101
0.1 mg
1.0 mg

Cor a 1.0103

Cor a 1.0103 represents an isoform of the Cor a 1 allergen from Corylus avellana, a member of the order Fagales that is found in the pollen. This allergen belongs to the family of Bet v 1 allergens known for members of this order of plants. This isoform is also called major pollen allergen Cor a 1.
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50900
50901
0.1 mg
1.0 mg

Fra e 1.0101

Fraxinus excelsior is member of the Oleaceae tree family, whose members are widely distributed throughout Europe. The pollen of this tree contains a major allergen of the so-called Ole e 1-like protein family, Fra e 1.0101.
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