DNA Topoisomerase I (Scl-70; full length)

Systemic Sclerosis / CREST Syndrome

Product Code Quantity Product Name Downloads Data Sheet
12500
12501
0.1 mg
1.0 mg

Centromere Protein B (CENP-B)

The centromere is a defined DNA region of a chromosome where the sister chromatids are connected and the attachment site of the kinetochore. Centromere protein B (CENP-B) binds to this DNA region and is involved in the assembly of the kinetochore.
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16900
16901
0.1 mg
1.0 mg

Centromere Protein A (CENP-A)

The centromere is a defined DNA region of a chromosome where the sister chromatids are connected and the attachment site of the kinetochore. Centromere Protein A (CENP-A) is a histone H3 variant defining the location and function of the centromeres.
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12400
12401
0.1 mg
1.0 mg

DNA Topoisomerase I (Scl-70; full length)

DNA Topoisomerase I is an enzyme that adjusts the supercoiling stage of DNA to resolve torsional stress occurring during DNA transcription and replication. Proteolytical processing matures the 100 kDa precursor into the 70 kDa form. Scl-70 full length corresponds to the 100 kDa precursor.
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14500
14501
0.1 mg
1.0 mg

DNA Topoisomerase I (Scl-70; truncated)

DNA Topoisomerase I is an enzyme that adjusts the supercoiling stage of DNA to resolve torsional stress occurring during DNA transcription and replication. Proteolytical processing matures the 100 kDa precursor into the 70 kDa form. Scl-70 truncated corresponds to the mature 70 kDa form.
INFO   
11500
11501
0.1 mg
1.0 mg

DNA Topoisomerase I (Scl-70; non recombinant; bovine)

DNA Topoisomerase I is an enzyme that adjusts the supercoiling stage of DNA to resolve torsional stress occurring during DNA transcription and replication. Proteolytical processing matures the 100 kDa precursor into the 70 kDa form.
INFO   
16000
16001
0.1 mg
1.0 mg

PM/Scl 100

The polymyositis/scleroderma (PM/Scl) complex is the human ortholog of the Saccharomyces cerevisiae exosome, which is involved in the processing and degradation of RNAs. PM/Scl 100 is one of the human subunits found in the nucleoplasm and, at higher concentrations, in the nucleolus.
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17000
17001
0.1 mg
1.0 mg

PM/Scl 75

The polymyositis/scleroderma (PM/Scl) complex is the human ortholog of the Saccharomyces cerevisiae exosome, which is involved in the processing and degradation of RNAs. PM/Scl 75 is one of the human subunits found in the nucleoplasm and, at higher concentrations, in the nucleolus.
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