Yersinia enterocolitica (O:9) LcrV

Yersiniosis

Product Code Quantity Product Name Downloads Data Sheet
43000
43001
0.1 mg
1.0 mg

Yersinia enterocolitica (O:8) YopM

Yersinia enterocolitica is a Gram-negative coccobacillus of which pathogenic serogroups, e.g. O:8, have been identified. Yersinia outer proteins (Yops) are key virulence factors during the infection of host cells. YopM is injected into the host cell’s cytosol where it interferes with the regulation of translation by activating ribosomal S6 kinase.
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43100
43101
0.1 mg
1.0 mg

Yersinia enterocolitica (O:9) LcrV

Yersinia enterocolitica serogroup O:9 is a causative agent of yersiniosis, a food-borne gastro-intestinal infection in humans. As part of the bacterial translocation apparatus, low calcium response V antigen (LcrV) is necessary for the secretion of Yersinia outer proteins (Yops) involved in host cell infection.
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43200
43201
0.1 mg
1.0 mg

Yersinia enterocolitica (O:9) YopB

Virulent isolates of Yersinia enterocolitica have been identified to cause gastroenteritis: yersiniosis. Yop B serves as an adapter protein and is necessary in pore-formation during infection. This enables delivery of Yop effectors into host cells.
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43300
43301
0.1 mg
1.0 mg

Yersinia enterocolitica (O:9) YopD

Upon the consumption of raw or undercooked contaminated food, humans can become infected with bacteria of the Yersinia enterocolitica serogroup O:9. During this infection, bacterial proteins are secreted to form pores in the host cell’s plasma membrane. Yersinia outer protein D (YopD) serves as an adapter protein in this process.
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43700
43701
0.1 mg
1.0 mg

Yersinia enterocolitica (O:9) YopE

A key virulence factor of pathogenic Yersinia enterocolitica strains is a plasmid-encoded type III secretion system, through which Yersinia outer proteins (Yops) are injected into the host cell. Yop E, a GTPase activation protein controls pore formation by activating small Rho GTPase, leading to inhibition of actin polymerization.
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43400
43401
0.1 mg
1.0 mg

Yersinia enterocolitica (O:9) YopH

To successfully infect human gastrointestinal cells, pathogenic Yersinia enterocolitica secrete and translocate various so-called Yersinia outer proteins (Yops) into host cells. Following translocation, the protein tyrosine phosphatase YopH (synonyme Yop51) affects signaling cascades by dephosphorylating host cell proteins.
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43500
43501
0.1 mg
1.0 mg

Yersinia enterocolitica (O:9) YopM

Besides Yersinia enterocolitica serogroups O:3 and O:8, serogroup O:9 is also pathogenic to humans and able to establish a gastrointestinal infection. During this process, Yersinia outer protein M (YopM) is actively injected into human cells where it activates ribosomal S6 kinase to manipulate host cell translation.
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43600
43601
0.1 mg
1.0 mg

Yersinia enterocolitica (O:9) YopN

Upon contact with a host cell, bacteria of the Yersinia enterocolitica serogroup O:9 secrete several effector proteins to establish an infection in humans. Yersinia outer proteins (Yops) are key virulence factors during the infection of host cells. YopN is involved in the prevention of the secretion of other Yops prior to contact to a host cell.
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